Conjugated estrogens. There are no restrictions on food, beverages, or activity while taking conjugated estrogens, tell your doctor if you are pregnant. You are taking antidepressants or a thyroid medication. Do not take conjugated estrogens if you are taking antidepressants or a thyroid medication. Long-term treatment with conjugated estrogens may increase your risk of developing endometrial hyperplasia, a condition that may lead to cancer of the uterus. Because Premarin can increase the risk of heart attack, and certain estrogen-dependent cancers, contact your doctor right away if you notice sudden shortness of breath or abnormal bleeding from the vagina.
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