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Metronidazole should not be used in the first trimester of pregnancy. Metronidazole should be stored at room temperature and protected from light. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. Metronidazole should be used with caution in patients with active or chronic severe peripheral and central nervous system diseases due to the risk of neurological aggravation. If the treatment is stopped too soon, the infection could still remain in body and if the treatment is prolonged a second infection may occur.
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